Genoa vs Lazio predictions & betting tips

Genoa and Lazio are set to clash at the Luigi Ferraris on Monday, 21 April 2025, in a Serie A encounter that balances survival against ambition. Genoa, currently 12th with 39 points, are aiming to cement their mid-table safety, while Lazio, sitting 6th on 56 points, are in hot pursuit of European qualification. With both sides having plenty to play for, this fixture promises high stakes and contrasting motivations.

Lazio have historically dominated this matchup, winning eight of the last 11 meetings. Genoa’s last home victory over the Biancocelesti dates back to 2019, highlighting their struggles in this rivalry. However, Genoa’s recent home resilience—unbeaten in their last six matches—could challenge the narrative. With an average of 2.2 goals per game between these sides, supporters can anticipate an intense and closely fought contest.

Form adds further intrigue to the mix. Genoa have been solid at home, turning defensive stability into valuable points, though they’ve often been held to draws. Lazio, meanwhile, have been inconsistent on the road, a vulnerability the hosts will look to exploit. Key players Andrea Pinamonti and Taty Castellanos, with eight and nine goals respectively, are likely to be central to their teams’ fortunes. Both sides also have a habit of scoring late, which could make for a dramatic finale.

This match is about more than just three points—it could define the season for both clubs. Genoa’s home advantage and late-scoring tendencies might inspire an upset, while Lazio’s European ambitions demand a commanding display. As the final whistle looms, the outcome could significantly shape their campaigns, making this a must-watch Serie A showdown.

Genoa - Lazio Key Facts

• Lazio Rome have a strong historical advantage over Genoa CFC, winning 21 out of the last 40 encounters, which highlights their dominance and makes them a more reliable choice for punters.

• Genoa CFC are unbeaten in their last six home matches, indicating a solid home form that could challenge Lazio Rome's away performance, making it crucial for betting considerations.

• Genoa CFC have not won any of their last three matches against Lazio Rome, including a recent 3-0 defeat, suggesting a psychological edge for Lazio that could influence the outcome of the upcoming match.

Betting Predictions

Primary bet: Over 2.5 goals @ 13/10

The Serie A fixture between Genoa and Lazio offers a promising opportunity for a high-scoring encounter. Current form and historical trends indicate a 67.74% likelihood of over 2.5 goals, supported by both teams' attacking patterns. Genoa have scored 38% of their goals and Lazio 34% in the final 15 minutes of matches, highlighting their ability to strike late. While their head-to-head meetings average 2.2 goals per match, the attacking momentum of both sides suggests this clash could exceed that figure, making the over 2.5 goals market an attractive option at 13/10.

Secondary bet: Away Win @ 5/4

For the secondary bet, Lazio's dominance in this fixture is a key factor. They have triumphed in 21 of their last 40 meetings with Genoa and remain unbeaten in their last three encounters. Additionally, Lazio have suffered just one defeat in their previous five Serie A matches against Genoa. While Genoa's home form this season (5-7-4) is respectable, Lazio's psychological edge and superior head-to-head record strengthen the case for an away win, which offers solid value at 5/4.