There are plenty of heavy hitters left in the Europa League this season as fans flock to their favourite crypto football betting platform to bet on which European giant will take home the crown.
Several of these clubs will believe they have what it takes to go all the way and lift the trophy, but which are leading the pack according to the bookies?
Based on the odds, the favourites to win the 2025-26 UEFA Europa League are:
Aston Villa (3/1 favourites)
After finishing second in the league phase, Aston Villa secured their spot in the round of 16 without having to compete in the play-offs.
The club knew going into the draw that they would face either Celta or Lille. Aston Villa was drawn against Lille, setting up a potential clash with top seed Lyon in the Europa League final, should both teams make it that far.
With Unai Emery at the helm, a specialist in winning this competition, it comes as little surprise that Aston Villa are many people's favourites to win the UEFA Europa League this season. At 3/1, they are the safe bet.
Lyon (7/1)
Lyon have a good chance in the Europa League this season, hence the 7/1 price tag. They have the technical quality to control games, the pace and athleticism to punish transitions, and the tactical flexibility to approach two-legged ties.
If they stay relatively healthy and defensively disciplined—and avoid giving away cheap goals—Lyon’s mix of match-winning quality and knockout-suited game plans is enough to beat “bigger” clubs over two legs and make a championship run plausible.
Roma (8/1)
Just behind Lyon are Serie A giants Roma, who the bookies are giving an 8/1 chance. Roma have a strong Europa League profile of experienced players, a tactically disciplined setup, and a defence comfortable protecting leads over two legs. They manage games well, slow matches down when needed, and are dangerous on set pieces, all of which could be key in tight knockout ties.
Having won a European trophy recently and reached the final of another, this is a club which has the guile and experience to go far in this competition. They will be one of the teams which nobody wants to play against.
Real Betis (8/1)
Real Betis have a credible Europa League pathway because their technical midfield and ball security can control tempo, limit chaos, and draw opponents out of shape. The bookies clearly see this organisational strength too, as they are backed at 8/1, joint third favourites of the 16 clubs remaining in the competition.
They’re comfortable switching between possession and can launch quick vertical attacks, which can be potent across two legs. In Seville, the Benito Villamarín provides a real home-leg edge, often turning tight ties.
As the competition heats up, fans and bettors alike will be eagerly watching the matches, cheering on their favourite teams, and placing their bets. The road to the final is set, and the favourites have been identified. Now, all that remains is to see how the matches unfold.
